Detta examensarbete dokumenterar arbetet med utveckling, införande och dokumentation av en nymetod för identitetsbestämning av farmaceutiska råvaror med röntgenfluorescens. Metoden ärutvecklad för att användas på laboratorier för kvalitetskontroll på AstraZeneca i Södertälje. Syftetmed arbetet var att utveckla en robust och effektiv metod samt att utbilda användarna i dethanteringssätt som krävs för att utföra snabba och korrekta analyser. Rapporten presenterarteknologin bakom röntgenfluorescensinstrument och vilka felkällor som kan påverka resultaten samtde pedagogiska teorier som använts för att beskriva det praktiska arbete som äger rum pålaboratoriet. Metoden och de försök som föregick metoden presenteras, och resultat och beslutdiskuteras.

The purpose of this thesis is to increase the understanding on how market leading pharmaceutical companies in Sweden limit the market share decrease when these companies patent expires. In order to respond to the purpose, two research questions have been asked: how do pharmaceutical companies deal with market strategies prior to the expiration of a patent: and how the market strategies is used when a patent has expired and as a consequence, generics entered the market. A case study was implemented based on two interviews with a brand manager and a therapy area manager within the company Pfizer AB in Sweden. The results suggest that pharmaceutical companies implement strategies in numerous ways which differs substantially from the theories, this having to do with Swedish legislation. The main aim with the execution of the strategy, before and after patent expiration is not to limit a decrease in market share hence, rather to retain the pharmaceutical companies strong brand image.

It generally takes 10 to 12 years for a new drug to hit the market. The pharmaceutical industry invests huge sums in these early stages of research and development. In spite of the rapidly rising research and development expenditures fewer and fewer blockbuster drugs are being developed. Longer lead times and aggressive generic post-patent competition have narrowed the timeframe for the pharmaceutical companies to profit on their investments.In the face of these threats the pharmaceutical industry has developed a battery of strategies to prolong market exclusivity and to maximize return on investment. These emerging strategies are commonly known as Life cycle management (LCM), which actually is more of a concept than a method.

In order to investigate the perceived Corporate Social Responsibility (CSR) concept and to indentify what expectations the key stakeholders have on the Pharmaceutical Industry both secondary and primary data has been used. CSR can be perceived as a corporate reputation enhancing tool, however it can also put pressure on corporations to behave as good corporate citizen responsible for thier stakeholders. All stakeholders´ interests therefore have to be consider in order to immprove corporate reputation..

This case study aims to explore how decision making is performed under circumstances characterised by high uncertainty. We have identified and interviewed two types of organisations dealing with investments in pharmaceutical drug development, a business characterised by high uncertainty. We have found that the two types of organisations we have interviewed display different decision making behaviour evaluating the same type of investment. Further we have explained these differences in decision making behaviour by using relevant decision making theories. This study has showed that different forms of decision making are appropriate depending on the conditions facing the decision maker..

De stora läkemedelsbolagen har sedan mitten på 1990-talet fått en ökad press på att optimera sina försörjningskedjor på grund av att patent på olika mediciner gått ut. När patentet gått ut kan generiska konkurrenter börja sälja liknande mediciner, de kan sälja dem till lägre pris eftersom de inte har forsknings och utvecklingskostnader att täcka. AstraZeneca tog i slutet av 1990-talet beslutet att implementera en ny strategi för deras försörjningskedja i deras produktion. Detta gjordes för att sänka deras produktionskostnader för att kunna konkurrera mot generiska konkurrenter. En konsultfirma togs in och Demand Driven Supply (DDS) implementerades.

The purpose of thesis was to investigate and compare how two companies within pharmaceutical industry and nuclear power industry are currently working with quality development regarding continuous improvement and Lessons Learned in business processes. In addition, a simple comparison was made with the automotiveindustry.McNeil AB are improving their processes continuously and are according to the findings of this report performing well in their pursuit of world-class pharmaceutical production. They have a well functioning process regarding improvements proposed in weekly improvement meetings engaging all employees. However, during interviews it was made clear that the functionality of the process which administer improvement proposals generated in addition to, or beside the weekly improvement meetings, were inadequate. McNeil AB is proposed to administer this through an IT solution instead of by paper and e-mail, that simplifies the process of adding, implementing and follow up an improvement proposal.The nuclear power plant Ringhals AB recently made major improvements in their business processes as well as the plant itself.

The purpose of this study is to describe the traceability of products that protect against counterfeiting and examine how protection against counterfeit products have been developed to date, and to display the opportunity to streamline the protection of products and brands.Nowadays, in the global world, it is getting increasingly more difficult to track the products. Especially for the last link in the chain, which in most cases is the customer and who is constantly exposed to risks. This report deals with the possibilities of preventing and detecting counterfeit products. Fake products are not unusual in an historical perspective. It has been common with counterfeits ever since the Middle Ages continuously until today. Forgers have become more skillful and they are successful in most industries. Many of the fake products are of poor quality and can be downright dangerous to the customer.To answer the question, the author used a qualitative collection method.

Parallel import in the European Union is the perfectly legal activity under Art. 28-30 EC of buying goods in a low-price country in order to ship and sell them in a high-price country. The pharmaceutical market in Europe is subject to the subsidiartiy principle of Art. 5 EC and heavily characterised by national regulations that lead to significant price differentials between – generally speaking – Northern and Southern Europe. This incites the activity of parallel traders in the first place, who act as arbitrageurs.

Parallel import in the European Union is the perfectly legal activity under Art. 28-30 EC of buying goods in a low-price country in order to ship and sell them in a high-price country. The pharmaceutical market in Europe is subject to the subsidiartiy principle of Art. 5 EC and heavily characterised by national regulations that lead to significant price differentials between ? generally speaking ? Northern and Southern Europe.

The purpose of this work is to do an investigation on the customers in the pharmaceutical sector; mainly general physicians who have taken part in the education events have any impact in their prescription behaviour after the participation in the program. The settings for this study are general practitioners in the Swedish market who have taken part in the education program held by Novo Nordisk in the treatment of diabetes disease. Methodology: The methodological approach adopted for this work is quantitative; using secondary data from the internal database from the company. The analytical model is tested through statistical analysis using the data?s obtained from the databases.

Abstract This paper discusses protectionism of intellectual property rights in general and the conflict between large pharmaceutical companies? rights to patent and developing countries? rights to cheap generic preparation in particular. The essay focuses above all on HIV/AIDS medicine. The description tries to give an image of the different interests that collide and why they collide. The different actors are above all the pharmaceutical branch, including researchers, inventors and salesmen with their economic interest of revenue, and the population of the development countries and their pressed situation considering the great need of medicine.

This Master of Science thesis was a part of Pharmadule Emtungas project to construct a mobile automated cell for welding of carbon steel pipe (Heating, Ventilation and Sanitation). Pharmadule Emtunga is using a modular building concept for building pharmaceutical factories. The modules contain these pipes. The goal of the thesis was to present concepts for technical solutions regarding welding methods and fixtures for the cell. Conceptual models for the cell were made with aid of CAD software.

Librarians like to think that libraries contribute substantially to the progress of research. However, libraries still seem to have serious problems getting integrated in their parent organization on equal terms with other parts of that organization. The degree of integration of the library is thus the main topic of this thesis and the purpose is to examine how the interaction between librarians and scientists is formed and can be developed. That issue leads to concrete questions concerning what part librarians play in the scientists work and which factors influence the cooperation or lack of cooperation. We have chosen, for reasons of comparison, to make two case studies; one is a branch of a university library and the other is a library in a large pharmaceutical company.

Problem: How is Lean, a production-focused model being applied to non-productive focused industries.Purpose: To examine how Lean has been applied to the department of Turbuhaler-Kvalitetskontroll and which parts have been successfully applied.Problem statement: How does the implementation of Lean?s basic concept, which originated in the car industry, differentiate itself from the implementation of Lean in the pharmaceutical industry, in this case the department of Turbuhaler-Kvalitetskontroll at AstraZeneca.Conclusions: The department has had success in its implementation of lean. They have developed and modified the basic concept in order to apply it and excluded the parts they did not consider necessary. Through their work they have accomplished numerous improvements in, among other things, the reduction of lead time. .